Study summary

Pilot randomized control trials (RCT) showed that inhaled sedative are safe and may shorten duration of ventilation and ICU stay. SAVE-ICU RCT is a large multicentre pragmatic RCT that aims to establish whether sedation with inhaled agents (intervention) compared to IV sedatives (control) improves patient outcomes (mortality, quality of life) and healthcare resource utilization (ICU- and hospital-free days) in patients with COVID and non-COVID ARDS (NCT04415060). While these trials may establish safety and efficacy of inhaled sedatives in critically ill patients, we need to understand the current barriers, facilitators and process that may affect the usability of these sedative in the ICU setting. Survey-SAVE-ICU study will use mixed methods (survey, small focus groups) to survey key stakeholders across Canada to answer this question.

Team List

Syeda Javeria Hasan

Angela Jerath

Brian Cuthbertson

Claudio Martin

Marat Slessarev

Neil Adhikari

Study publications

Coming soon